AI4Life: A European Success for Artificial Intelligence in the Life Sciences
21 January 2026
AI4Life: A European Success for Artificial Intelligence in the Life Sciences
The AI4Life project, co-led by Florian Jug (Computational Biology Research Centre at Human Technopole) and Anna Kreshuk (EMBL), received the highest possible score in the European Commission’s final review, recognising its scientific impact and the quality of its achievements in applying artificial intelligence to biological image analysis.
Born from a European collaboration within the Euro-BioImaging infrastructure and funded by the Horizon Europe programme between 2022 and 2025, AI4Life addressed one of the major challenges in modern biological research: making AI accessible and usable for non-specialist researchers, overcoming technical complexity and the fragmentation of existing solutions.
At the heart of the scientific outcomes recognised by the EU review is the BioImage Model Zoo, a crowd-sourced repository of pre-trained deep learning models for microscopy image analysis, designed to be immediately usable by biologists and microscopists without advanced computational skills. The platform provides interoperable and standardised models, drastically reducing the time needed to deploy high-quality AI tools in laboratory practice.
In addition to the Model Zoo, the project developed infrastructures such as the BioEngine and services for data management according to the FAIR principles (Findable, Accessible, Interoperable, Reusable), contributing to a sustainable ecosystem for the adoption of artificial intelligence in biology.
This outstanding evaluation confirms Human Technopole’s leading role in creating open, integrated AI tools for the scientific community and emphasises the importance of international collaboration and interdisciplinary approaches to address complex challenges in biological research.
Lorenzo Calviello and his group of the Human Technopole’s Research Centres for Genomics and Computational Biology have been awarded a five-year My First AIRC Grant by Fondazione AIRC per la Ricerca sul Cancro. The grant provides over €99,000 for 2026, for a total of €500,000, to support a project aimed at identifying cancer-specific proteins that could serve as new immunotherapy targets in colorectal cancer.
Human Technopole researchers have identified the molecular mechanisms by which the membrane receptor sortilin binds thyroglobulin along its pathway to the release of thyroid hormones within the thyroid gland. The results of the research were published in Nature Communications and highlight that sortilin senses thyroglobulin via a short flexible “tag” which appears to be a common motif for the recognition of other partner proteins throughout our body.
The Giustacchini Group of the Genomics Research Centre of Human Technopole has been awarded a €1.66 million grant from the Fondo Italiano per la Scienza (FIS 2) to advance precision immunotherapy for haematological malignancies. The three-year project, titled “Tailoring Precision Immunotherapy to Haematological Malignancies”, aims to develop more effective cell-based therapies for blood cancers by integrating molecular, cellular and systems-level analyses.
Turning scientific discoveries into real-world therapies was the focus of the second international conference “Future Trends in Translational Medicine – From Molecules to Therapies,” held at the Complesso Universitario di San Giovanni a Teduccio in Naples on 30 -31 October 2025.
As 2025 comes to a close, we look back at a year shaped by connection, discovery and growth. At Human Technopole, progress happens when perspectives meet, between disciplines, technologies and people. Our holiday card captures this idea visually: what looks like a festive forest is actually a colon under the microscope, a structure that changes depending on how you look at it, reminding us that science often begins with a shift in perspective.
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