Dollie LaJoie
- Research Group Leader, LaJoie Group
Dollie studied the process of nuclear envelope formation in human cells for her PhD under the supervision of Katharine Ullman in the department of Oncological Sciences at the University of Utah. She then became an Alexander von Humboldt postdoctoral fellow in the lab of Alexander von Appen at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany where she worked to biochemically characterize protein-protein interactions of membrane- and actin-remodeling proteins. As a research group leader at the Human Technopole, Dollie combines her excitement for cell biology and the technical expertise she gained during her postdoctoral research to investigate coordinate regulation of the nuclear envelope environment and the cytoskeleton in disease. Mutations in nuclear envelope proteins cause certain subtypes of muscular dystrophy and cardiomyopathy which are characterized by disrupted nuclear-cytoskeletal coupling. Understanding the molecular mechanisms underpinning these disease states will improve clinical insight.
