This service enables researchers to explore the potential of single-molecule techniques and develop new protocols and workflows. Prior experience with dynamic single-molecule (DSM) approaches is not required.
The unit is equipped with two state-of-the-art instruments:
- C-Trap ‘Dymo’ utilizes confocal scanning and is primarily used for imaging in solution.
- C-Trap ‘Edge’ offers the flexibility to switch between wide-field fluorescence and TIRF imaging. Additionally, it allows label-free imaging via IRM, making it ideal for studies close to the surface.
The unit provides support for a wide range of experimental approaches.
This service will only be performed by NF staff, ideally accompanied by the User. As part of this service, the NF staff will check sample quality, troubleshoot, and define optimal conditions for data acquisition. If possible, an automation protocol for the experiment can be developed to streamline future data collection. The User can spend up to 10 days in the NF, testing various samples. The work can be split into two visits. The outcome of this service is an established protocol that can be used for ‘data acquisition’ service.