Structural biology

Coscia Group


Available PostDoc, PhD and internship positions – informal enquiries are welcome.


Our Research

The thyroid gland is a natural bioreactor where rare iodine from the diet is accumulated and used to synthesise thyroid hormones, essential iodinated molecules for the metabolism and development in all vertebrates.

In humans, thyroid disfunction severely impacts cardiovascular homeostasis, metabolism, brain development and function, with increasing incidence Worldwide. Currently, our understanding of molecular events behind thyroid hormone synthesis is far from complete and consequently of major thyroid diseases. We use an integrative structural biology approach to visualise thyroid processes across scales, from atoms to organoids. Our results will unveil how a healthy thyroid works and how its function is altered in specific diseases, such as auto-immune diseases, congenital hypothyroidism and thyroid cancers. In the long term, this research lays basis towards improving diagnosis and treatment of major thyroid disorders. Human Technopole gives us a great opportunity to reach this goal at The Centre for Structural Biology with an excellent, international environment and cutting-edge scientific facilities.

EMAIL CONTACT: francesca.coscia[at]


Coscia Group 2023

Coscia Group Publications



2021 ERC starting grant


Swiss National Science Foundation (SNSF)


Human Frontier Science Program (HFSP)



    • Dario Guerrini: Bachelor Student Bicocca University
    • Giacomo Palm: Postgraduate Research Assistant
    • Angelica Critelli: Visiting Scientist Istituto Auxologico Hospital
    • Carlo Corneo: MSc student
    • Camilla Stejskalova: MSc student and Postgraduate fellow
    • Federica Miele, MSc Student

Group members