Human technopole Milan

Highlights

  • OPEN HT: a dialogue with the scientific community

    Today Monday 19 December from 10.00 a.m. in the Human Technopole Auditorium at MIND Milano Innovation District OPEN HT took place. The event represented an opportunity for dialogue between the life sciences Institute and the national scientific community. The initiative was also the occasion to share the developments of Human Technopole as detailed in the […]

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  • How APOE4 affects human brain in Alzheimer’s disease

    Apolipoprotein E (APOE) is a small protein encoded by the APOE gene regulating lipid homeostasis in mammals.  The e4 variant of the APOE gene (APOE4) is associated with an increased risk of developing Alzheimer’s disease (AD) in mammals. A Nature study co-authored by Jose Davila-Velderrain reveals cell-type specific effects of APOE4 on cholesterol metabolism and […]

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  • Exploring The ‘Dark Matter’ Of Colorectal Cancer

    An international study co-ordinated by Andrea Sottoriva, Head of Human Technopole’s Computational Biology Research Centre, together with researchers from the Institute for Cancer Research (ICR) in London, reveals that key changes that explain mechanistic aspects of the onset and development of intestinal tumours come not only from genetic mutations, but also from so-called ‘epigenetics’ and […]

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Research at HT

Improving human health and well-being is the ultimate goal of Human Technopole. We need to prevent and cure diseases to allow people of all ages to not only live longer, but also live better.

Discover more about our:

Thanks to a global and interdisciplinary study of human biology, our research is aimed at understanding the mechanisms at the basis of various diseases, leveraging the technological advances of the last decade and the enormous amount of biological, clinical and socio-economic data currently available to improve our healthcare systems and our overall quality of life.

Human Technopole’s research is based on five interdisciplinary research centres: Genomics, Neurogenomics, Structural Biology, Computational Biology and Health Data Science. Research activity is supported by six state-of-the-art facilities.

External Training

The overarching and inspiring theme for HT’s external training activities is to create a centre of excellence for training promising researchers in the biomedical sciences, while enabling broad access to HT’s expertise, methods and resources.

Work with us

We offer the opportunity to be part of a new, dynamic research institute promoting a highly collaborative and international working environment.

We aim to attract the best resources in each field with a selection based on merit and transparency as we believe that highly diverse teams produce the best and most innovative results.

If you are a passionate person who likes to seize great challenges, consider applying for one of our scientific or administrative vacancies. 

Latest news

To keep up to date with Human Technopole’s development and the activities of the institute, sign up to our newsletter. The HT newsletter is sent every three months or so to share what is happening at HT: news, events, scientific and dissemination initiatives, job and training opportunities and much more.
  • CRISPRcleanR WebApp makes your life easier with CRISPR-Cas9 screens

    A web-based application developed by the Iorio Group and the IT & digitalisation team at Human Technopole helps non-computational scientists process and analyse CRISPR-Cas9 screens by reducing false-positive hits. CRISPR/Cas9 technology has become the gold standard for genome and epigenome editing, for studying the regulation of gene expression, and for high-throughput screenings aiming at identifying […]

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  • Human technopole Milan

    The second edition of our Integrated Report

    The second edition of our Integrated Report covering the year 2021, is now online.  The Report is an important tool through which Human Technopole communicates its commitment to social responsibility, based on transparent, accurate and complete information. Our hope is that this can help promote trust towards the work carried out by Human Technopole and […]

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  • OPEN HT: a dialogue with the scientific community

    Today Monday 19 December from 10.00 a.m. in the Human Technopole Auditorium at MIND Milano Innovation District OPEN HT took place. The event represented an opportunity for dialogue between the life sciences Institute and the national scientific community. The initiative was also the occasion to share the developments of Human Technopole as detailed in the […]

    Read more
  • Introducing Ivano Legnini

    Ivano Legnini is an Italian molecular and systems biologist interested in gene regulation. He currently lives in Berlin, working at the Max Delbrück Center – Berlin Institute for Medical Systems Biology, in the lab of Nikolaus Rajewsky. Ivano did his PhD in the lab of Irene Bozzoni at Sapienza University of Rome, where he also […]

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  • How APOE4 affects human brain in Alzheimer’s disease

    Apolipoprotein E (APOE) is a small protein encoded by the APOE gene regulating lipid homeostasis in mammals.  The e4 variant of the APOE gene (APOE4) is associated with an increased risk of developing Alzheimer’s disease (AD) in mammals. A Nature study co-authored by Jose Davila-Velderrain reveals cell-type specific effects of APOE4 on cholesterol metabolism and […]

    Read more
  • Measuring chromatin compaction with FRET-FISH

    DNA intercalating dyes and massively sequencing techniques are traditionally used to study nuclear chromatin compaction. These tools, however, do not allow for direct measurement of chromatin compaction of individual loci. Nicola Crosetto and Magda Bienko combine fluorescence resonance energy transfer (FRET) with DNA fluorescence in situ hybridization (FISH) to assess the level of chromatin compaction […]

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  • Exploring The ‘Dark Matter’ Of Colorectal Cancer

    An international study co-ordinated by Andrea Sottoriva, Head of Human Technopole’s Computational Biology Research Centre, together with researchers from the Institute for Cancer Research (ICR) in London, reveals that key changes that explain mechanistic aspects of the onset and development of intestinal tumours come not only from genetic mutations, but also from so-called ‘epigenetics’ and […]

    Read more
  • From risk to resilience in mental health and developmental diversity

    World-leading interdisciplinary research groups have committed to provide innovative approaches to improve the quality of life of individuals with neurodevelopmental disorders Paris, 25th October 2022 The consortium of the EU-funded project Risk and Resilience in Developmental Diversity and Mental Health (R2D2-MH) is kicking-off today in Paris. 26 European and associated partners (Australia, Canada and Israel) […]

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  • Bridging Artificial Intelligence and Machine Learning with bioimage analysis

    The AI4Life project launched today, marks an exciting chapter in the computational and life science research communities. The €4 million Horizon Europe funded project aims to create accessible, harmonized, and interoperable AI tools and methods for solving today’s microscopy image analysis problems. The gap Machine learning (ML) has accelerated frontier research in the life sciences, […]

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  • Message by President Verona and CdS

    Milan, 24 September 2022  Dear Researchers  on behalf of the Consiglio di Sorveglianza of the Foundation that I chair, I would like to confirm that I have received and read with great attention the letter addressed to us in recent days by hundreds of Italian researchers, in which they reaffirm the great interest that the […]

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