Highlights

  • How colorectal cancer escapes from the immune system early on

    An international study co-led by scientists from Human Technopole reveals that colorectal tumours use both genetic and epigenetic strategies to evade immune detection almost immediately after they transform into cancerous. The results, published in Nature Genetics, challenge previous notions that immune evasion occurs gradually over time.

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  • Human Technopole awarded grant to create 3D models of rare brain cancer 

    Human Technopole researchers Nereo Kalebic and Blagoje Soskic have been awarded $1,319,010 by the Gilbert Family Foundation (GFF) through the Next-Generation NF1 Models Initiative. Their funded project “Assembloid Platform to Model Cellular Interactions Driving NF1 Glioma Pathology” focuses on developing the first 3D cell culture model of Neurofibromatosis type 1 (NF1), a genetic cancer predisposition syndrome that affects the central and peripheral nervous systems and increases the risk of high-grade gliomas.

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  • Human Technopole’s National Facilities: New Call Opens with +36% in Proposals so far

    Human Technopole’s National Facilities have launched their third round of access, starting 1 October 2025, inviting researchers to submit proposals for access to cutting-edge technologies in genomics, genome engineering, structural biology, light imaging, and data analysis. The opening comes in a context of strong momentum: since mid-2024, the National Facilities have received 293 proposals in total, with a 36% rise between the pilot and the first call, granting access to 184 projects with a success rate above 60%.

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Research at HT

Improving human life and technology by investing in human health and prevention research is the ultimate goal of Human Technopole. We need to prevent and cure diseases to allow people of all ages to not only live longer, but also live better.

To accomplish its mission, HT’s research strives to unravel fundamental mechanisms relevant to human physiology and disease using a multi-scale systems biology approach, based on a combination of experimental research and theory, coupled with computational biology and Artificial Intelligence.

Shared Research Infrastructure

To fulfil the needs of the Italian life science research community, HT infrastructure includes 5 National Facilities, serving as technological hubs and incubators for developing and disseminating new tools and methodologies and for carrying out top-level research.

Courses and Conferences

The overarching and inspiring theme for HT’s external training activities is to create at HT a centre of excellence for training promising researchers in the biomedical sciences, while providing broad access to HT’s expertise, methods, and resources to the external community. Courses and conferences are supported by institutional and external funding, and sponsorships are welcome.

Work with us

We offer the opportunity to be part of a new, dynamic research institute promoting a highly collaborative and international working environment.

We aim to attract the best resources in each field with a selection based on merit and transparency as we believe that highly diverse teams produce the best and most innovative results.

If you are a passionate person who likes to seize great challenges, consider applying for one of our scientific or administrative vacancies.