The Volumetric EM service provides segmentation and analysis of structures in serial EM section data. This service is restricted to segmentation and analysis of a finite number of structures per image (ie, mitochondria, organelles, vesicles, other similar objects of study). The proposal must include specific examples of the structure(s) of interest in order to judge feasibility. This service includes, but is not necessarily limited to, the following use-cases:
- Data pre-processing: de-streaking, alignment, contrast adjustment.
- Data annotation: generating dense labels covering structures of interest for the purpose of training AI algorithms.
- Model Development: Training and deployment of AI segmentation algorithms specific to the research question.
- Downstream Analysis: Analysis of segmented structures, morphology, number, distribution.
While these are examples of the services we can provide, we anticipate that most projects will require some combination of tools and services and so we will work with successful Applicants to craft pipelines that fulfil their analysis needs, as well as provide training and support in their future use. Our ethos is to work openly and transparently with our Users in the spirit of scientific collaboration. During the application phase, it will only be necessary to describe the data and the desired form of the analysis result; the precise details of the analysis will be discussed with the Applicants upon selection of the project.