Point-scanning confocal microscope with multiphoton excitation and Airyscan2 detector, 5 laser lines (405 nm, 488 nm, 561 nm, 594 nm, and 639 nm), multiphoton excitation with a tunable Ti:Sa laser (700 nm – 1300 nm) and a fixed (1040 nm) laser line, 6 non-descanned detectors (4 PMT and 2 BiG), epifluorescence excitation and sCMOS camera.