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Tubulin posttranslational modifications through the lens of new technologies

The Tubulin Code revolutionizes our understanding of microtubule dynamics and functions, proposing a nuanced system governed by tubulin isotypes, posttranslational modifications (PTMs) and microtubule-associated proteins (MAPs). Tubulin isotypes, diverse across species, contribute structural complexity, and are thought to influence microtubule functions. PTMs encode dynamic information on microtubules, which are read by several microtubule interacting proteins and […]

Rare diseases: Telethon-Cariplo funds two research projects at HT

Two research projects from Human Technopole have won the Fondazione Telethon and Cariplo grant to uncover the genetic and molecular mechanisms of acute myeloid leukemia and congenital adrenal hyperplasia. The projects, led by Alice Giustacchini (Group Leader of Genomics) and Emanuele Villa and Nicolò Caporale (Testa Group, Neurogenomics), have been respectively funded with €230,000 and €250,000.