Andrea Graziadei
- Senior Manager - Structural Proteomics, National Facility for Structural Biology
Andrea Graziadei is a structural biologist and structural bioinformatician specializing in integrative modelling and crosslinking mass spectrometry.
SHORT CV:
Since 2022 Senior Manager, structural proteomics SSU – Human Technopole
2019-2022 PostDoc – Technische Universität Berlin (Berlin, DE)
Mentor: Prof. Juri Rappsilber
2019 PhD in structural biology – European Molecular Biology Laboratory, (Heidelberg, DE)
Mentor: Dr. Teresa Carlomagno
Contacts
Publications
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05/2020 - eLife
The guide sRNA sequence determines the activity level of box C/D RNPs
2’-O-rRNA methylation, which is essential in eukaryotes and archaea, is catalysed by the Box C/D RNP complex in an RNA-guided manner. Despite the conservation of the methylation sites, the abundance of site-specific modifications shows variability across species and tissues, suggesting that rRNA methylation may provide a means of controlling gene expression. As all Box C/D […]
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