Emily Georgiades
- Postdoc, Bienko Group
Here at the Human Technopole I am working as postdoc in molecular and computational biology as part of the Bienko group. My project aims to address an exciting unexplored hypothesis that transcription factors are spatially organised within the cell nucleus, forming radial gradients that likely play an important role in regulating gene expression. To investigate this hypothesis I am generating new omics datasets throughout cellular differentiation and employing multi-omics data integration methods with an aim to elucidate this novel mechanism.
I graduated with a PhD from the Wellcome Trust Genomic Medicine and Statistics DPhil programme at the University of Oxford in 2023 where I worked in Professor Jim Hughes’ lab who specialise in gene regulation. My PhD project was titled “Dynamics in the Regulatory Genome”, in which I was investigating the role of cohesin in regulating 3D genome architecture. I combined genome engineering, live-cell imaging, genomics and computational analysis to develop a novel method to capture the dynamic process of cohesin recruitment and migration.
In 2017 I graduated from the University of Bath with a first-class MSci in Natural Sciences, majoring in Chemistry with Biology, with an industrial placement year in the Human Genetics department at Pfizer.
