Gaia Perone

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Publications

  • 09/2024 - Nature Methods

    Serialized on-grid lift-in sectioning for tomography (SOLIST) enables a biopsy at the nanoscale

    Cryo-focused ion beam milling has substantially advanced our understanding of molecular processes by opening windows into cells. However, applying this technique to complex samples, such as tissues, has presented considerable technical challenges. Here we introduce an innovative adaptation of the cryo-lift-out technique, serialized on-grid lift-in sectioning for tomography (SOLIST), addressing these limitations. SOLIST enhances throughput, […]