Lucia Prandi

Publications

  • 07/2026 - BioRxiv

    Insulin synthesis is sustained by Tent5 poly(A) polymerases

    Insulin is an essential regulator of glucose homeostasis in vertebrates, and impairment of its synthesis or action leads to diabetes with severe health complications in humans. It is therefore essential to understand how beta cells control insulin synthesis and secretion, including the transcription, translation and decay of its messenger RNA. Using sequencing-based poly(A) tail length […]