Paolo Swuec
- Head of National Facility for Structural Biology, National Facility for Structural Biology
As Head of the National Facility for Structural Biology at Human Technopole, I am responsible for coordinating a comprehensive platform for structural characterization across scales covering sample preparation, specimen characterization and imaging. I am also primarily responsible for running the Facility’s Cryo-EM Unit, which is capable of state-of-the-art multi-flavoured electron microscopy (single-particle, single-cell, electron tomography and CLEM).
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09/2024 - Nature Methods
Serialized on-grid lift-in sectioning for tomography (SOLIST) enables a biopsy at the nanoscale
Cryo-focused ion beam milling has substantially advanced our understanding of molecular processes by opening windows into cells. However, applying this technique to complex samples, such as tissues, has presented considerable technical challenges. Here we introduce an innovative adaptation of the cryo-lift-out technique, serialized on-grid lift-in sectioning for tomography (SOLIST), addressing these limitations. SOLIST enhances throughput, […]