Philipp Sebastian Erdmann
- Research Group Leader, Erdmann Group
Philipp Erdmann is a chemical biologist and microscopist. After five years as a project group leader at the MPI for Biochemistry, Martinsried, he joined HT in February 2021.
Philipp’s lab will focus on the analysis of liquid-liquid phase separation (LLPS) effects using in situ cryo-electron tomography. LLPS is often involved in crucial processes of both transmittable and non-transmittable human diseases, including virus infections and neurodegenerative disorders.
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Publications
- 11/2021 - BioRxiv
In situ architecture of the ciliary base reveals the stepwise assembly of IFT trains
he transition zone, then as it extends into the cytosol, first the dynein-1b and then the IFTA densities are missing. This suggests the IFTB backbone is built first, followed by IFTA and then dynein-2 recruitment. Kinesin-2 is relatively small and flexible and so could not be identified by cryo-ET. Instead, the authors use expansion microscopy […]