Samuel Edward Lacey


  • 08/2022 - BioRxiv

    The Molecular Structure of Anterograde Intraflagellar transport trains

    Anterograde intraflagellar transport trains are essential for cilia assembly and maintenance. These trains are formed of 22 IFTA and IFTB proteins that link structural and signalling cargoes to microtubule motors for import into cilia. It remains unknown how the IFTA/B proteins are arranged into complexes and how these complexes polymerise into functional trains. Here, we […]