Sebastiano Pasqualato

Protein crystallographer, structural biologist, biochemistry and biophysics aficionado. After a Ph.D. in “crystallographie biologique” (Université Paris XI and CNRS), as I approached the end of my post-doc (IEO, Milan), I realized my inclination towards collaborative efforts and a focus on the biochemical, biophysical, and crystallographic aspects of the projects I worked on. This led me to a position as head of the Structural Biology and Biochemistry Unit of the European Institute of Oncology and subsequently as Manager of Biophysics at the Structural Biology Research Centre in Human Technopole.

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  • 11/2023 - Cell Reports Medicine

    RAGE engagement by SARS-CoV-2 enables monocyte infection and underlies COVID-19 severity

    The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has fueled the COVID-19 pandemic with its enduring medical and socioeconomic challenges because of subsequent waves and long-term consequences of great concern. Here, we chart the molecular basis of COVID-19 pathogenesis by analyzing patients’ immune responses at single-cell resolution across disease course and severity. This […]