Role of inherited genetic variants in rare blood cancer uncovered
Combining three different sources of genetic information has allowed researchers to further understand why only some people with a common mutation go on to develop rare blood cancer
Hundreds of new targets accelerate cancer drug discovery
The second generation of the Cancer Dependency Map uncovers 370 priority drug targets, with strong links to specific cancer types.
Members of the CIVP appointed
The Consiglio di Sorveglianza of the Human Technopole Foundation has appointed eight experts with proven professional qualifications to form the Standing Independent Evaluation Committee (CIVP).
Two ERC-funded projects to search for tumours’ weaknesses
Human Technopole has once again been awarded by Europe’s prestigious public body for funding of scientific research conducted within the European Union, the European Research Council (ERC), for two projects on the origin of tumours, their evolution and the development of resistance to therapies. The two studies could contribute to the identification of new anti-cancer targeted treatments.
COVID-19: How SARS‑CoV‑2 Enters Human Cells
A study by the University of Padua and Human Technopole, together with the University of Milan and the European Institute of Oncology, published in Cell Reports Medicine, reveals that SARS-CoV-2, the virus that causes COVID-19, binds the RAGE receptor present on the surface of specific human immune cells to penetrate them and pathologically alter their function. This study also shows how the involvement of RAGE, previously known only in the context of other pathophysiological conditions, such as obesity and diabetes, is implicated in the degree of severity with which COVID-19 can manifest.