Neurogenesis and brain development require a tightly regulated balance between symmetric and asymmetric division of neural stem and progenitor cells. How such balance is maintained is unclear: the Taverna and Kalebic Groups now show that the activity of the chromatin modifier DOT1L controls brain neurogenesis by modulating asparagine metabolism in apical progenitor cells.

The beginning of summer means warmer days, longer hours and holiday planning. Students in Italy are officially on holiday, but their learning continues!

Human Technopole is offering up to 21 fully funded 4-year PhD scholarships to young scientists from the national and international community who wish to undertake a doctoral degree on a project focused on Computational Biology, Structural Biology, Genomics and Neurogenomics. We encourage applications from highly motivated graduates with outstanding academic qualifications. Successful candidates will join […]

The Consiglio di Sorveglianza of the Human Technopole Foundation has approved the implementation of five National Facilities, intended as infrastructural facilities with a high technological impact, available to the national research community. As prescribed by the Convenzione stipulated pursuant to Law 160/2019, the approval follows a two-stage public consultation process: the first stage involved representatives […]

More than 80 immune-mediated diseases have been identified to date. However, it is unclear whether the same genetic factors underpin their onset. By coupling statistical methods with genome-wide association studies (GWAS), the Soskic group has shown that diverse immune-mediated diseases have distinct genetic patterns that converge on activating the same cells and signalling pathways. Immune-mediated […]