Zuccolo Group
In the Zuccolo group, epidemiologists, statisticians and data scientists analyse highly-dimensional complex data to improve our understanding of maternal and child health, with a particular focus on intergenerational effects. We develop new data pipelines and phenotype captures, while applying cutting edge methods for robust inference to inform knowledge translation. We describe health and health behaviours trends and trajectories emerging in contemporary populations, study their determinants, identify predictors of vulnerability and risk, and investigate how families and particularly parent-offspring interactions, shape individuals’ health and wellbeing. The resulting evidence will help to prioritise and inform the design of family-level or parent-focussed interventions to support maternal, child, and adolescent health.
FUNDING
MSCA Postdoctoral Fellowship – Albert Navarro Gallinad
ALUMNI
- Molly Van der Heiden: Bristol Medical School student intern
- Elham Bahari Kheirjoui: Università degli Studi di Milano MSc student intern
Group members
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Luisa Zuccolo
Research Group Leader -
Maeregu Woldeyes Arisido
Postdoc -
Alice Sofia Calvello
Undergraduate Intern -
Sandra Mickwitz
Undergraduate Intern -
Albert Navarro Gallinad
Health Data Scientist -
Valeria Nazzari
PhD Student -
Linda Repetto
Genetic Epidemiologist
Publications
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10/2024 - The Lancet Regional Health: Europe
COVID-19 diagnosis, vaccination during pregnancy, and adverse pregnancy outcomes of 865,654 women in England and Wales: a population-based cohort study
Background The extent to which COVID-19 diagnosis and vaccination during pregnancy are associated with risks of common and rare adverse pregnancy outcomes remains uncertain. We compared the incidence of adverse pregnancy outcomes in women with and without COVID-19 diagnosis and vaccination during pregnancy. Methods We studied population-scale linked electronic health records for women with singleton […]
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08/2024 - Nature Human Behaviour
The genetic landscape of neuro-related proteins in human plasma
Understanding the genetic basis of neuro-related proteins is essential for dissecting the molecular basis of human behavioural traits and the disease aetiology of neuropsychiatric disorders. Here the SCALLOP Consortium conducted a genome-wide association meta-analysis of over 12,000 individuals for 184 neuro-related proteins in human plasma. The analysis identified 125 cis-regulatory protein quantitative trait loci (cis-pQTL) and […]
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08/2024 - The Lancet Regional Health: Europe
COVID-19 vaccination and birth outcomes of 186,990 women vaccinated before pregnancy: an England-wide cohort study
Background COVID-19 vaccination in pregnancy is recommended by the World Health Organisation as effective and safe. However, there remains a lack of robust evidence to inform vaccination choices for women of childbearing potential in relation to their future pregnancies. Here we investigated the association between starting a course of COVID-19 vaccination before pregnancy and birth […]
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08/2024 - Alcohol: Clinical and Experimental Research
Trends in fetal alcohol spectrum disorder research: A bibliometric review of original articles published between 2000 and 2023
Fetal alcohol spectrum disorder (FASD) is a leading cause of neurodevelopmental disability globally. International organizations have highlighted an urgent need for improved prevention, diagnosis, and support. However, the evidence base needed to inform this is thought to be limited. We conducted two complementary reviews to (i) describe trends in the volume and characteristics of original […]
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