In a long interview on Panorama della sanità – a specialist magazine aimed at doctors and healthcare managers – Director Iain Mattaj spoke about the Human Technopole project, stressing the principle of collaboration that underlies it and its prospects.
Human Technopole, a leading biomedical and life sciences research institute based in Milan, is seeking three highly qualified candidates to join its Management Committee, the governing body responsible for the operational leadership of the Foundation.
PRECISE (Predictive Relationships Explaining Cancer Genetic Interactions and Synthetic Essentiality) is a pan-European initiative that aims to move cancer research beyond cataloguing cancer vulnerabilities towards predicting them before they are experimentally tested. Human Technopole (HT) is among the founding partners of the consortium, with Francesco Iorio leading its scientific activities across the institute alongside other HT research groups. The consortium and its scientific vision are presented in a Nature Genetics commentary.
Researchers at Human Technopole have developed a novel machine learning-based method that transforms composite fluorescence microscopy images with overlapping signals into separate images revealing individual cellular structures. The tool is published in Nature Methods, with experimental models and training data openly available on GitHub.
The mechanisms of life are complex. What happens at the molecular level shapes cells, tissues, organs and entire organisms. To understand human biology, and what drives disease, we need to connect these different scales rather than study them in isolation. That is our approach at Human Technopole.
In a large international collaboration, Human Technopole has contributed to the development of three complementary risk prediction models that estimate heart failure risk across the entire cardiovascular disease spectrum. Together, these tools enable transparent, data-driven risk assessment and support personalised treatment strategies and more sustainable healthcare delivery.
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