09 September 2022

Human Technopole Studies Neurological and Psychiatric Effects of Covid-19

The international research project ‘NEUROCOV’ on the long-term neurological and psychiatric effects of COVID-19 has kicked off. The five-year EU-funded project was developed by Human Technopole and the German Centre for Neurodegenerative Diseases (DZNE) and involves ten institutes from seven countries. Human Technopole, which will receive EUR 3.2 Million European Commission funding, will be engaged […]

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06 September 2022

Human stem cells recapitulate early embryonic development in vitro

Differentiation of pluripotent stem cells (PSCs) has successfully been used to study tissue and organ development in vitro. Eleonora Conti and Oliver Harschnitz review the pros and cons of using human PSCs to investigate the development of placodes – embryonic structures giving rise to diverse organs – during the early steps of human embryonic development […]

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04 August 2022

Derailing molecular cargo trains in cilia makes them turn around

Researchers at the Human Technopole and Max Planck Institute of Molecular Cell Biology and Genetics show how molecular cargo trains change direction in cellular micro-antennas. Cilia are antenna-like structures that protrude outwards from the surface of eukaryotic cells. Misassembled cilia in humans can cause numerous diseases from infertility to lung malfunction. The assembly and maintenance […]

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02 August 2022
Cilia trains

Cilia in 3D: Miniature train station discovered

Cilia are hair-like organelles that extend from most eukaryotic cells and perform many functions, including motility and signaling. Together with collaborators at the University of Geneva (Hamel-Guichard lab) and Biozentrum, University of Basel (Engel Lab), Dr. Gaia Pigino’s Group at the Human Technopole in Milan has now revealed that cilia have a specialised transport hub […]

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