Francesco Iorio’s intervention starts from estimated numbers- in the course of one’s life, 1 out of 2 people will develop some form of cancer – and from the observation that, unfortunately, at the moment, there are still too few targeted drugs capable of defusing the vital mechanisms of cancer, attacking it selectively and without causing severe side effects.
Recently, new frontiers for personalised medicine are opening up thanks to
advances in genomic editing, big data of various kinds – biomedical and non biomedical and genomic – and the reduction of molecular profiling costs. These aspects are allowing scientists to make great steps in the discovery of new therapeutic targets and related molecular markers for predicting therapeutic response in patients. We are therefore witnessing a paradigm shift in the development of new anti-cancer drugs, which promises enormous benefits for cancer patients and their quality of life.
Which brain connections coordinate the sense of sight with movement, for example maintaining stable vision while walking or moving our eyes? How is cholesterol formed and what functions does it have in its intermediate steps? These are the topics of the research projects awarded the Early Career Fellowship Programme, a call for proposals launched by […]
The first symposium on “Gender Equality and Diversity at HT” took place today at the Human Technopole Auditorium. The aim of the event was to discuss why there are differences in the career outcomes of men and women and how we can act to promote equality and inclusion at HT. During the event we heard from Gerlind […]
The Supervisory Board of the Human Technopole Foundation has appointed Marino Zerial as the institute’s new Director. Currently Director of the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany, a research institution he helped found over 25 years ago, Marino Zerial is also an honorary professor at the Faculty of Medicine […]
Magda Bienko, Group Leader at the Functional Genomics Centre at Human Technopole has been awarded an ERC Consolidator Grant for her research project “Radialis”. The project, which has earned a funding of 2 million euros, aims to understand the design principles shaping genome architecture. Within our cells, DNA is folded in a three-dimensional structure. The […]
A web-based application developed by the Iorio Group and the IT & digitalisation team at Human Technopole helps non-computational scientists process and analyse CRISPR-Cas9 screens by reducing false-positive hits. CRISPR/Cas9 technology has become the gold standard for genome and epigenome editing, for studying the regulation of gene expression, and for high-throughput screenings aiming at identifying […]
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