New Human Technopole Strategic Plan 2024-2028 now online!
Five years since its inception, Human Technopole is now a dynamic institute where researchers from around the world have laid the foundations for unravelling the fundamental mechanisms of life across multiple biological scales – molecules, cells, tissues, organs, organisms, populations – in space and time.
Over the next few years Human Technopole will aim to consolidate the achieved results and continue pursuing its mission to improve human life and technology by focusing on four main objectives:
1) to foster fundamental cutting-edge research on human biology and human health;
2) to provide shared infrastructures, the National Facilities, to the national scientific community;
3) to offer advanced scientific training to scientists;
4) to enable the exploitation of research and technological innovation results via technology transfer.
The National Facilities in particular represent an important innovation promoted by our founding Ministries to support Italy’s scientific research through cutting edge technologies which, for the first time, will be made available to researchers throughout the country.
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Human Technopole’s National Facilities: new Call for Access now Open
The new call for Access to the National Facilities services is now open! The Human Technopole’s National Facilities continue to expand their support for cutting-edge research by launching the first Call for Access of 2025. Building on the success of the 24-PILOT call, to which over 120 projects have applied, this new opportunity allows researchers to benefit from state-of-the-art technologies and expertise.
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Childhood Cancer: Free DNA in Blood Reveals Therapy Resistance
An international study coordinated by Milan’s Human Technopole, the Institute of Cancer Research (ICR) in London, and the Royal Marsden Hospital in London has shown that certain DNA fragments found in the blood of paediatric cancer patients can be used as “biomarkers” to obtain information on the characteristics of the disease and its ability to resist therapies. Analysing these fragments could represent an effective alternative to tumour tissue biopsy, a practice that is particularly difficult in children.
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Human Technopole at the Quirinale: Advancing Innovation with MIND
Human Technopole is honoured to have participated in today’s meeting at the Quirinale, where President of the Republic Sergio Mattarella welcomed a delegation from MIND on the occasion of the tenth anniversary of the universal exposition Milano EXPO 2015.
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Exploring Nuclear Proteomics with the PRUNE Project
Meet Carlos Jimenez, Postdoc in the Bienko Group (Genomics), who has been awarded a prestigious Marie Skłodowska-Curie Actions Postdoctoral Fellowship from the European Union. The grant, totalling €172,750.08 and covering a two-year period, will support his groundbreaking project PRUNE – Uncovering the Proteomic Radial Organisation within the Eukaryotic Nucleus – to study how the spatial arrangement of nuclear proteins contributes to optimal cell functioning.
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The “tubulin code” in control of molecular train logistics in cilia
By developing a sophisticated in vitro system coupled with advanced imaging techniques and CRISPR genome editing, an international team of researchers from Human Technopole (Italy) and the TUD Dresden University of Technology (Germany) shows that tubulin tyrosination/detyrosination regulates the bidirectional IFT train movement and avoids collision between trains moving in opposite directions along the cilium. The research was funded by the ERC and the DFG “Physics of Life” Excellence Cluster. The results are published in Nature Communications.