New paper by Francesco Iorio on Molecular Systems Biology
07 July 2020
New paper by Francesco Iorio on Molecular Systems Biology
A new study by Francesco Iorio – Group Leader, Research Centre for Computational Biology – published in Molecular Systems Biology has created the most comprehensive analysis for understanding how cancer drugs work at a molecular level by combining drug response data with CRISPR genetic screens across hundreds of cancer cell lines.
The research identified the mechanism-of-action in 50 per cent of the 397 drugs tested. This improved understanding of the biological mechanisms underpinning drug response will facilitate faster, more efficient development of new cancer drugs and brings us closer to precision medicine for cancer patients.
An international group of light microscopists provides guidelines on how to process raw microscopy images and assemble them for publication in a standardised and reproducible manner.
The Pigino Group developed a detailed protocol to obtain super-resolution images of the green alga Chlamydomonas reinhardtii by using conventional optical light microscopes.
The Pigino Group presents a CRISPR/Cas-based protocol for the targeted insertion of exogenous genes in the unicellular green alga Chlamydomonas that is amenable to rapid high-throughput screening of mutant cells.
Meet Rodrigo Pracana, Senior Bioinformatician at the Functional Genomics Computation Scientific Service Unit of the Genomics Research Centre – Functional Genomics programme.
Manage Cookie Consent
This website uses technical cookies to provide you with a better browsing experience and, subject to your consent, profiling cookies to offer you information and advertising in line with your preferences. For more details, you can consult our cookie policy by clicking on the link below, or set your preferences by clicking "set preferences". By selecting "accept cookies" you consent to the use of all types of cookies while you can revoke your consent by clicking on "refuse". By deciding to refuse or closing the banner, only the technical cookies necessary for the correct functioning of the site will be activated.
Technical cookies (required)
Always active
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Third party cookies for statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Third party cookies for profiling
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.