New paper by Francesco Iorio on Molecular Systems Biology
A new study by Francesco Iorio – Group Leader, Research Centre for Computational Biology – published in Molecular Systems Biology has created the most comprehensive analysis for understanding how cancer drugs work at a molecular level by combining drug response data with CRISPR genetic screens across hundreds of cancer cell lines.
The research identified the mechanism-of-action in 50 per cent of the 397 drugs tested. This improved understanding of the biological mechanisms underpinning drug response will facilitate faster, more efficient development of new cancer drugs and brings us closer to precision medicine for cancer patients.
More info here: https://www.embopress.org/doi/full/10.15252/msb.20199405
Share:
You could also like:
-
Checklists for preparation and analysis of microscopy images
An international group of light microscopists provides guidelines on how to process raw microscopy images and assemble them for publication in a standardised and reproducible manner.
-
Ultrastructure Expansion Microscopy details Chlamy native organisation
The Pigino Group developed a detailed protocol to obtain super-resolution images of the green alga Chlamydomonas reinhardtii by using conventional optical light microscopes.
-
Welcome to our new Director Marino Zerial
On 1 September 2023 the Human Technopole community warmly welcomed Marino Zerial as he officially took office as the institute’s new Director.
-
Knocking-in Chlamydomonas reinhardtii genes with CRISPR/Cas
The Pigino Group presents a CRISPR/Cas-based protocol for the targeted insertion of exogenous genes in the unicellular green alga Chlamydomonas that is amenable to rapid high-throughput screening of mutant cells.
-
Exploring HT Research with Rodrigo Pracana from Genomics
Meet Rodrigo Pracana, Senior Bioinformatician at the Functional Genomics Computation Scientific Service Unit of the Genomics Research Centre – Functional Genomics programme.