The “tubulin code” in control of ciliary beating
Using advanced cryo-electron microscopy techniques and mutational analysis, HT researchers show that protofilament-specific patterns of tubulin polyglutamylation and glycylation promote the direct binding of axonemal proteins to the ciliary axoneme, thus modulating ciliary beating. The findings are published in Current Biology.
The evolutionary history of amylase genes for starch digestion
A Nature study co-authored by HT researchers reveals that amylase genes required for starch digestion underwent multiple duplication and deletion events during human evolution and that agriculture favoured structures containing amylase gene duplications.
HT Welcomes the Scientific Community with the New External Seminar Series
We are pleased to announce the launch of the Human Technopole External Seminar Series, an initiative dedicated to bringing leading researchers from around the world on campus. These scientists, working in various life sciences disciplines, will share their latest research and insights with the HT and external scientific community.
The National Facility for Light Imaging with Nicola Maghelli
Meet Nicola Maghelli, Head of the National Facility for Light Imaging at Human Technopole. The National Facility for Light Imaging is equipped with several high-end microscopy systems and instruments that enable both internal and external scientists to explore the microscopic world by imaging single cells and their components with high spatial and temporal resolution, potentially enhancing our understanding of diseases and paving the way for new therapies.
The Genetic Landscape of Neuro-Related Proteins
An international collaboration between Human Technopole, Fudan University, the University of Edinburgh, and the SCALLOP Consortium identified hundreds of proteins in human plasma related to human behavioural traits and neuropsychiatric disorders. These proteins are potential targets for drug repurposing and novel therapeutic interventions for mental disorders. The findings are published in Nature Human Behaviour.
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