5 fully funded PhD scholarships at HT through the SEMM
Human Technopole is offering up to 5 fully funded PhD scholarships to young scientists from the national and international community who wish to undertake a doctoral degree on a project focused on Computational Biology, Structural Biology or Biophysical modelling.
Multiscale investigation of 7q11.23 copy number variation in neurodevelopmental disorders
Using diverse omics approaches and multiscale disease modelling, Human Technopole researchers uncovered the effects of 7q11.23 CNV, a section of chromosome 7 on neuronal differentiation, gene expression, protein synthesis, and intrinsic neuronal excitability in two neurodevelopmental disorders (i.e., Williams-Beuren and 7q microduplication syndromes). The research results are published in The Journal of Clinical Investigation.
Engineered Parasite Delivers Therapeutic Proteins to Central Nervous System
Engineering a parasite, Toxoplasma gondii, which is naturally suited to cross the blood-brain barrier and enter neuronal cells, so that it can deliver therapeutic proteins to the central nervous system: this is the result of a study by an international group of scientists, including researchers from the University of Milan and Human Technopole, recently published in Nature Microbiology.
Mechanism of ciliary train switch and cargo recognition
A study by the Pigino Group at Human Technopole reveals that the conversion from anterograde to retrograde intraflagellar transport requires the complete disassembly of anterograde trains at the ciliary tip and provides the mechanisms for direction-specific cargo binding and transport in cilia.
The National Facility for Structural Biology with Paolo Swuec
Meet Paolo Swuec, responsible for running the Italy’s first Cryo-EM Facility and, today, Head of the National Facility for Structural Biology at Human Technopole: a hub for cutting-edge research, facilitating the structural characterization of biological entities, ranging from tissues to amino acid side-chains.
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