President Simoni talks about the importance of Human Technopole to strengthen Italy’s scientific research capacity.
02 May 2020
President Simoni talks about the importance of Human Technopole to strengthen Italy’s scientific research capacity.
In a wide article on Gli Stati Generali, President Marco Simoni covered numerous issues concerning the current situation, including the importance of platforms such as Human Technopole to strengthen the country’s scientific research capacity.
Professor Simoni highlighted that one of the aims of Human Technopole is to strengthen Italy’s research capacity in the field of life sciences, also offering scholars outside the institute to use its technologies. Technological development in various sectors – not only in the life sciences – can become an element of economic growth. An example of this is when a discovery is made: “for it to be truly useful, it must also be industrialised. This produces new jobs and further investment,” Professor Simoni explained.
Other aspects highlighted in the article were the need to implement the functioning of research centres, to invest in scientific facilities of various kinds, so that tools can be developed to address prepared challenges such as Covid19.
The Glastonbury Group is among the recipients of the Data Insights Cycle 3 awards. The aim of the grant is to develop a machine learning model that identifies disease-relevant cell subpopulations whilst predicting a phenotype/disease of interest from large-scale single-cell RNA-seq data.
In collaboration with an international team of scientists, HT researchers identified a missense mutation in a gene involved in brain-intrinsic immunity as the genetic cause of SARS-CoV-2 brainstem encephalitis.
A study by Human Technopole, the Institute of Cancer Research and the Royal Marsden NHS Foundation Trust in London has shown that in prostate cancer the presence in the same tumour of cells with large differences in shape and genetic composition indicates an increased risk of relapse, including after a decade. The study may help doctors better tailor treatment for this disease, adopting more aggressive therapies in cases where these parameters indicate a higher risk of disease recurrence.
Human Technopole is opening its National Facilities, providing advanced equipment and technologies accessible through calls for proposals open to the Italian scientific community. Projects will be selected by a commission of international experts. Scientists will have access to five new dedicated facilities, which act as catalysts for open innovation in the life sciences sector, crucial for research and the health of Italians.
An international team of scientists led by HT researchers Magda Bienko and Nicola Crosetto developed an open-source software for deconvolution of widefield fluorescence microscopy image stacks and large tissue scans. This new tool increases the information obtained with fluorescence microscopy-based spatial omic methods.
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