On 1 September 2023 the Human Technopole community warmly welcomed Marino Zerial as he officially took office as the institute’s new Director.
Following 25 years in Dresden where he served as Director of the Max Planck Institute of Molecular Cell Biology and Genetics, Marino was appointed as Human Technopole Director in February 2023 by the Foundation’s Consiglio di Sorveglianza following a global call for applications managed by a Search Committeee composed of international experts.
Over the past few months, he has visited Milan and Human Technopole on multiple occasions to meet with HT Faculty and Scientific Committee and coordinate a smooth transition with his predecessor prof. Iain Mattaj.
Among the first priorities of his Directorate are the drafting of a new Strategic Plan for 2024-2028, the opening of National Facilities to the national research community and the expansion of the HT campus with the construction of the new building.
The Glastonbury Group is among the recipients of the Data Insights Cycle 3 awards. The aim of the grant is to develop a machine learning model that identifies disease-relevant cell subpopulations whilst predicting a phenotype/disease of interest from large-scale single-cell RNA-seq data.
In collaboration with an international team of scientists, HT researchers identified a missense mutation in a gene involved in brain-intrinsic immunity as the genetic cause of SARS-CoV-2 brainstem encephalitis.
A study by Human Technopole, the Institute of Cancer Research and the Royal Marsden NHS Foundation Trust in London has shown that in prostate cancer the presence in the same tumour of cells with large differences in shape and genetic composition indicates an increased risk of relapse, including after a decade. The study may help doctors better tailor treatment for this disease, adopting more aggressive therapies in cases where these parameters indicate a higher risk of disease recurrence.
Human Technopole is opening its National Facilities, providing advanced equipment and technologies accessible through calls for proposals open to the Italian scientific community. Projects will be selected by a commission of international experts. Scientists will have access to five new dedicated facilities, which act as catalysts for open innovation in the life sciences sector, crucial for research and the health of Italians.
An international team of scientists led by HT researchers Magda Bienko and Nicola Crosetto developed an open-source software for deconvolution of widefield fluorescence microscopy image stacks and large tissue scans. This new tool increases the information obtained with fluorescence microscopy-based spatial omic methods.
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