11/2019 - O2S2: A new venue for computational geostatistics

Applied sciences have witnessed an explosion of georeferenced data. Object oriented spatial statistics (O2S2) is a recent system of ideas that provides a solid framework where the new challenges posed by the GeoData revolution can be faced, by grounding the analysis on a powerful geometrical and topological approach. We shall present a perspective on O2S2, […]

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10/2019 - Spatial heterogeneity in non-parametric efficiency: An application to Italian hospitals

This paper introduces a new empirical procedure for the estimation of hospitals’ technical efficiency in presence of spatial heterogeneity. We propose a methodology that allows treating spatial heterogeneity independently of a predetermined reference to administrative borders. We define geographical spatial regimes, characterised by spatial proximity and homogeneity of relevant demand characteristics, within which to assess […]

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09/2019 - Association rule mining to identify transcription factor interactions in genomic regions

Genome regulatory networks have different layers and ways to modulate cellular processes, such as cell differentiation, proliferation, and adaptation to external stimuli. Transcription factors and other chromatin-associated proteins act as combinatorial protein complexes that control gene transcription. Thus, identifying functional interaction networks among these proteins is a fundamental task to understand the genome regulation framework.

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