Chiara Ambrosini
Pubblicazioni
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09/2025 - Cell Reports
Adducins regulate morphology and fate of neural progenitors during neocortical neurogenesis
The evolutionary expansion of the mammalian neocortex is driven by increased proliferative capacity of neural progenitor cells. However, the molecular machinery controlling the proliferation of apical and basal progenitors during neocortical development remains poorly understood. Here, we show that the three actin-associated morpho-regulatory adducins (ADD1–3) underlie the abundance of basal progenitors in the developing ferret […]
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01/2024 - Current Protocols
Optimized and Scalable Precoating-Free Reprogramming of Human Peripheral Blood Mononuclear Cells into iPSCs
Human disease modeling has been profoundly transformed by the introduction of human induced pluripotent stem cells (iPSCs), marking the onset of a new era. This ground-breaking development offers a tailored framework for generating pluripotent cells from any individual, effectively enabling the development of cellular models for the study of human physiology and diseases on an […]