
Giovanni Faga
- Head of Automation – Automated Stem Cell and Organoid Facility, Facility automatizzata per cellule staminali e organoidi
Contatti
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Pubblicazioni
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11/2020 - Molecular Autism
High-throughput screening identifies histone deacetylase inhibitors that modulate GTF2I expression in 7q11.23 microduplication autism spectrum disorder patient-derived cortical neurons
Background Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental condition affecting almost 1% of children, and represents a major unmet medical need with no effective drug treatment available. Duplication at 7q11.23 (7Dup), encompassing 26–28 genes, is one of the best characterized ASD-causing copy number variations and offers unique translational opportunities, because the hemideletion of […]