Jacopo Zasso
- Senior Technician, Piattaforma Nazionale di Editing Genomico e Modelli di Malattia
Esperto di cellule staminali coinvolto nella riprogrammazione delle cellule somatiche e nel differenziamento 2D-3D in una varietà di destini neurali e nella traduzione di questi processi in automazione. Esperienza in sistemi di cellule staminali pluripotenti e neurali, come generarle e sfruttarle per chiarire i meccanismi di sviluppo e degenerativi.
Contatti
Segui
Pubblicazioni
-
07/2026 - BioRxiv
Insulin synthesis is sustained by Tent5 poly(A) polymerases
Insulin is an essential regulator of glucose homeostasis in vertebrates, and impairment of its synthesis or action leads to diabetes with severe health complications in humans. It is therefore essential to understand how beta cells control insulin synthesis and secretion, including the transcription, translation and decay of its messenger RNA. Using sequencing-based poly(A) tail length […]
-
01/2024 - Current Protocols
Optimized and Scalable Precoating-Free Reprogramming of Human Peripheral Blood Mononuclear Cells into iPSCs
Human disease modeling has been profoundly transformed by the introduction of human induced pluripotent stem cells (iPSCs), marking the onset of a new era. This ground-breaking development offers a tailored framework for generating pluripotent cells from any individual, effectively enabling the development of cellular models for the study of human physiology and diseases on an […]