Ludovica Proietti

Pubblicazioni

• 02/2026 - FEBS Letters

  Genetic interactions, synthetic lethality and complexity in cancer vulnerability mapping—Insights and perspectives from the 2nd EuroDepMap symposium

  Large-scale perturbational approaches have transformed cancer research, enabling systematic identification of tumour-specific dependencies and therapeutic vulnerabilities. However, many clinically relevant vulnerabilities arise from genetic interactions, including synthetic lethal and buffering relationships, and are shaped by cellular state, lineage and treatment history. Interpreting complex dependency landscapes increasingly relies on advanced computational and AI-based approaches integrating molecular, […]

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