Highlights
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Shedding light on the molecular mechanisms of Gabriele-de Vries Syndrome
Using advanced stem cell models, Human Technopole researchers show how mutations in the YY1 gene cause widespread dysregulation of genes crucial for brain development in multiple cell types, leading to structural abnormalities and impaired neuronal function. The results of the research are published in the Nature Portfolio journal Molecular Psychiatry.
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Human Technopole Commitment to Gender Equality
Human Technopole is proud to announce the launch of its new Gender Equality Plan (GEP) for 2025-2027, a strategic initiative designed to further integrate gender equality across all aspects of the Institute, building upon the successful outcomes of the previous GEP (2022-2024). HT has also achieved the UNI/PdR 125:2022 certification, which recognizes organizations that promote gender equality and foster inclusive workplaces.
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2 fully funded PhD fellowships at HT through SISSA
Human Technopole is offering 2 fully funded 4-year PhD fellowships to young scientists from the national and international community who wish to undertake a doctoral degree on a project focused on Computational Biology.
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Advancing Precision Immunotherapy for Paediatric Leukaemia with Alice Giustacchini and her Group
Meet Alice Giustacchini, Research Group Leader in Population and Medical Genomics. Her project, titled “Tailoring Precision Immunotherapy to Paediatric Acute Myeloid Leukaemia,” aims to study the cellular and molecular dynamics of CAR-T cell therapy in blood cancers.
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Human Technopole’s National Facilities: new Call for Access now Open
The new call for Access to the National Facilities services is now open! The Human Technopole’s National Facilities continue to expand their support for cutting-edge research by launching the first Call for Access of 2025. Building on the success of the 24-PILOT call, to which over 120 projects have applied, this new opportunity allows researchers to benefit from state-of-the-art technologies and expertise.
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Human Technopole at the Quirinale: Advancing Innovation with MIND
Human Technopole is honoured to have participated in today’s meeting at the Quirinale, where President of the Republic Sergio Mattarella welcomed a delegation from MIND on the occasion of the tenth anniversary of the universal exposition Milano EXPO 2015.
Research at HT


Improving human life and technology by investing in human health and prevention research is the ultimate goal of Human Technopole. We need to prevent and cure diseases to allow people of all ages to not only live longer, but also live better.
To accomplish its mission, HT’s research strives to unravel fundamental mechanisms relevant to human physiology and disease using a multi-scale systems biology approach, based on a combination of experimental research and theory, coupled with computational biology and Artificial Intelligence.
Shared Research Infrastructure
To fulfil the needs of the Italian life science research community, HT infrastructure includes 5 National Facilities, serving as technological hubs and incubators for developing and disseminating new tools and methodologies and for carrying out top-level research.
Courses and Conferences
Work with us


We offer the opportunity to be part of a new, dynamic research institute promoting a highly collaborative and international working environment.
We aim to attract the best resources in each field with a selection based on merit and transparency as we believe that highly diverse teams produce the best and most innovative results.
If you are a passionate person who likes to seize great challenges, consider applying for one of our scientific or administrative vacancies.