Human Technopole

An international collaborative study led by Human Technopole, Candiolo Cancer Institute IRCCS in Turin, the University of Turin, and the Wellcome Sanger Institute in Cambridge (UK) has identified new factors associated with therapeutic response in colorectal cancer. The research has led to the development of a machine-learning model capable of accurately predicting the effects of cetuximab, a drug in clinical use, on different colorectal tumour subtypes. Funded by the AIRC Foundation, the study paves the way to identifying molecular features that could serve as biomarkers for predicting treatment response in patients with this type of cancer.

A Long Non-Coding RNA Identified as a Potential Therapeutic Target for Multiple Myeloma: Collaborative AIRC Study by University of Magna Graecia and Human Technopole Published in Blood.

A multidisciplinary team led out of the ADAPT Centre at Trinity College Dublin has published cutting-edge research on a new tool designed to enable efficient data linkages between rare diseases and environmental datasets. Published recently in Nature Digital Medicine, the researchers present SERDIF (Semantic Environmental and Rare Disease data Integration Framework), an innovative framework that enables health data researchers to efficiently link environmental and health data sources through location and time information.

The Human Technopole External Seminar Series features leading scientists from various fields, including genomics, neurogenomics, structural biology, computational biology, health data science, biophysical modelling, and molecular cell biology.

Researchers from Human Technopole, the Institute of Molecular Biotechnology and Bicocca University established a method for developing brain assembloids that allows reproducing salient aspects of the antero-posterior polarity of the human cerebral cortex in vitro and opens new possibilities for disease modelling. The study is published in Nature Methods.

Human Technopole takes part in the European Researchers Night in Milan on 27 September. Through interactive workshops, experiments, and scientific demonstrations, especially aimed at younger audiences, the event seeks to bring citizens closer to science in a fun and engaging way.