Human Technopole’s Director Marino Zerial was invited last week to give the Lectio Magistralis during the inauguration ceremony of University of Genoa’s academic year 2023-2024.
“Building networks is the only way we can aim to solve major problems and challenges. In this sense, HT’s National Facilities represent a unique opportunity to bring added value to the Italian life sciences ecosystem and support the creation of a strong and internationally competitive national community” underlined Director Zerial during his presentations entitled “Human Technopole, the open innovation hub for life sciences” which opened the academic year at the University of Genoa, outlining the upcoming challenges for medical research.
Director Zerial’s presentation provided students and institutions present at the inauguration with an overview of the current status of the HT project as well as the institute’s new research mission aimed at unravelling fundamental mechanisms of biological systems, relevant to human disease, using a multi-scale systems biology approach. Human Technopole researchers will therefore investigate the emergent properties of biological systems across scales and how these evolve.
The lectio was also an opportunity to share information on the upcoming National Facilities, which will support the national community by providing access to state-of-the-art infrastructure, training opportunities and technology development. In turn this will support the development of scientific collaborations with HT researchers and increase the impact of Italian research worldwide.
The inauguration ceremony included welcoming remarks by University of Genoa Rector Federico Delfino, President of the Conference of Rectores of Italian Universities (CRUI) Giovanna Iannantuoni as well as a musical tribute to Fabrizio de André.
An international collaborative study led by Human Technopole, Candiolo Cancer Institute IRCCS in Turin, the University of Turin, and the Wellcome Sanger Institute in Cambridge (UK) has identified new factors associated with therapeutic response in colorectal cancer. The research has led to the development of a machine-learning model capable of accurately predicting the effects of cetuximab, a drug in clinical use, on different colorectal tumour subtypes. Funded by the AIRC Foundation, the study paves the way to identifying molecular features that could serve as biomarkers for predicting treatment response in patients with this type of cancer.
The Human Technopole Director, Marino Zerial, has been awarded the 2024 Mercurio Prize in the “Research and Development” category, in recognition of the excellence of his research in the field of cell biology. Zerial, renowned for his studies on the mechanisms of endocytosis and cellular transport, has made significant contributions to the understanding of cellular dynamics, with potential therapeutic applications for diseases such as liver conditions.
Researchers from Human Technopole, the Institute of Molecular Biotechnology and Bicocca University established a method for developing brain assembloids that allows reproducing salient aspects of the antero-posterior polarity of the human cerebral cortex in vitro and opens new possibilities for disease modelling. The study is published in Nature Methods.
Meet Clelia Peano, Head of the National Facility for Genomics. The Facility offers cutting-edge services to develop robust experimental and analytical workflows to explore different genomic research areas, including DNA and RNA analysis, chromatin structure, and epigenetic mechanisms regulating transcription. The goal is to enhance genomic research in all its aspects, benefiting the entire Italian scientific community.
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