Highlights

  • The “tubulin code” in control of molecular train logistics in cilia

    By developing a sophisticated in vitro system coupled with advanced imaging techniques and CRISPR genome editing, an international team of researchers from Human Technopole (Italy) and the TUD Dresden University of Technology (Germany) shows that tubulin tyrosination/detyrosination regulates the bidirectional IFT train movement and avoids collision between trains moving in opposite directions along the cilium. The research was funded by the ERC and the DFG “Physics of Life” Excellence Cluster. The results are published in Nature Communications.

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Research at HT

Improving human life and technology by investing in human health and prevention research is the ultimate goal of Human Technopole. We need to prevent and cure diseases to allow people of all ages to not only live longer, but also live better.

To accomplish its mission, HT’s research strives to unravel fundamental mechanisms relevant to human physiology and disease using a multi-scale systems biology approach, based on a combination of experimental research and theory, coupled with computational biology and Artificial Intelligence.

Shared Research Infrastructure

To fulfil the needs of the Italian life science research community, HT infrastructure includes 5 National Facilities, serving as technological hubs and incubators for developing and disseminating new tools and methodologies and for carrying out top-level research.

Courses and Conferences

The overarching and inspiring theme for HT’s external training activities is to create at HT a centre of excellence for training promising researchers in the biomedical sciences, while providing broad access to HT’s expertise, methods, and resources to the external community. Courses and conferences are supported by institutional and external funding, and sponsorships are welcome.

Work with us

We offer the opportunity to be part of a new, dynamic research institute promoting a highly collaborative and international working environment.

We aim to attract the best resources in each field with a selection based on merit and transparency as we believe that highly diverse teams produce the best and most innovative results.

If you are a passionate person who likes to seize great challenges, consider applying for one of our scientific or administrative vacancies.