Ossola and Kalebic. Frontiers in Neuroscience 2022 The cerebral cortex – the outer brain layer – accounts approximately for half of the human and mammalian brain mass and controls language, memory, reasoning, and consciousness. Specialised cortex cells – the neural progenitors – are responsible for the specification, positioning and maturation of neurons in the cortex, […]

A research project that focuses on the thyroid and its function, proposed by Dr Francesca Coscia of Human Technopole, has been awarded with an ERC Starting Grant, one of the most important European grants supporting young scientists at the beginning of their independent research career. Francesca, a Group Leader in the Human Technopole Structural Biology […]

2021 was a year of “firsts” for Human Technopole: our first 100 employees (a number we will soon double!), the opening of our first lab spaces, the first Early Career Fellows, scientific training and outreach activities, the first visits on campus by key stakeholders, our first Integrated Reporting and, last but not least, a new address.  We hope you continue to enjoy following our updates and activities. We are excited […]

The nucleus of eukaryotic cells contains the genome of an organism, which consists of chromosomal DNA arranged in well-organised protein-DNA structures. To proliferate, cells first duplicate their chromosomal DNA and then distribute it evenly between to daughter cells by means of a multistep process referred to as cell cycle. During cell division or mitosis, the […]

Retrotransposons or transposable elements (TEs) are parts of eukaryotic DNA that can replicate and paste themselves into different locations in the genome. The process involves reverse transcription converting RNA into DNA, which is then inserted into the host genome. This “copy-and-paste” mechanism is shared with a class of viruses called retroviruses but does not lead […]