Convenzione HT: first round of consultations underway
29 July 2021
Convenzione HT: first round of consultations underway
The Convenzione signed on 30 December 2020 between the Ministry of Economy and Finance, the Ministry of Health, the Ministry of University and Research and the Human Technopole Foundation regulates the creation of National Facilities (NFs) at HT, to be made available to the Italian scientific community to conduct high quality research in their respective fields, independent of institutional affiliation.
The Convenzione foresees that such National Facilities will be identified through a two-stage consultation process: the first phase addressed to selected stakeholders representing the life science research system, the second to the entire scientific community.
The first phase kicked off on 23 July as a questionnaire was sent to a list of representatives of Universities, research hospitals, research centres, research funding organisations and the life science industry identified by the Convenzione’s Technical Committee. The Committee is composed of two Director Generals of the Ministry of Health and the Ministry of University and Research, one Italian delegate of ESFRI, the Chair of Human Technopole’s Scientific Advisory Board and the Director of Human Technopole.
The questionnaire, largely based on the form used by ESFRI to collect proposals for research infrastructures to be included in the European roadmap, will allow to identify the national life science community’s perceived priorities with regard to research infrastructures and to collect adequately motivated proposals for possible National Facilities to be implemented at Human Technopole.
The indications resulting from this first phase will then be made available for feedback to the Italian scientific community during a second round of consultations to take place in the autumn of 2021.
In collaboration with an international team of scientists, HT researchers identified a missense mutation in a gene involved in brain-intrinsic immunity as the genetic cause of SARS-CoV-2 brainstem encephalitis.
A study by Human Technopole, the Institute of Cancer Research and the Royal Marsden NHS Foundation Trust in London has shown that in prostate cancer the presence in the same tumour of cells with large differences in shape and genetic composition indicates an increased risk of relapse, including after a decade. The study may help doctors better tailor treatment for this disease, adopting more aggressive therapies in cases where these parameters indicate a higher risk of disease recurrence.
Human Technopole is opening its National Facilities, providing advanced equipment and technologies accessible through calls for proposals open to the Italian scientific community. Projects will be selected by a commission of international experts. Scientists will have access to five new dedicated facilities, which act as catalysts for open innovation in the life sciences sector, crucial for research and the health of Italians.
An international team of scientists led by HT researchers Magda Bienko and Nicola Crosetto developed an open-source software for deconvolution of widefield fluorescence microscopy image stacks and large tissue scans. This new tool increases the information obtained with fluorescence microscopy-based spatial omic methods.
HT researchers are part of an international team of scientists that discovered genetic clues to the cause of restless leg syndrome, a condition common among older adults. The finding could help identify those individuals at greatest risk of the condition and point to potential ways to treat it.
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