Human Technopole is now an Associate Partner of LifeTime, the pan-European research initiative that aims to revolutionise healthcare by tracking and understanding human diseases at single cell resolution to transform patients’ care and the sustainability of healthcare systems.
Joining the LifeTime community is an important opportunity for Human Technopole to build a strategic network of relevant European partners that share our ambition and goals.
Human Technopole’s mission is fully aligned with LifeTime’s overarching aim to tackle complex human diseases. Specifically, the three defining pillars of LifeTime (single-cell multiomics, organoids and machine learning-based deconvolution) are represented in HT by the close integration of Centres and Core Facilities featuring leading expertise in these fields.
Together with the University of Milan, the European Institute of Oncology (IEO) and the Sacco Hospital, Human Technopole is already part of the Italian branch of the initiative Lifetime for COVID19, which for the upcoming two years will be led by the Head of our Research Centre for Neurogenomics, Prof. Giuseppe Testa.
The LifeTime consortium gathers over 120 leading scientists from over 90 European research institutes. The University of Milan is the Italian partner of the consortium and other Italian associate partners include the European Institute of Oncology, Fondazione Istituto FIRC di Oncologia Molecolare, the Institute for Biomedical Technologies and the Institute of Photonics and Nanotechnologies of the Italian National Research Council as well as many prominent Italian universities.
An international study coordinated by Milan’s Human Technopole, the Institute of Cancer Research (ICR) in London, and the Royal Marsden Hospital in London has shown that certain DNA fragments found in the blood of paediatric cancer patients can be used as “biomarkers” to obtain information on the characteristics of the disease and its ability to resist therapies. Analysing these fragments could represent an effective alternative to tumour tissue biopsy, a practice that is particularly difficult in children.
Human Technopole is honoured to have participated in today’s meeting at the Quirinale, where President of the Republic Sergio Mattarella welcomed a delegation from MIND on the occasion of the tenth anniversary of the universal exposition Milano EXPO 2015.
Meet Carlos Jimenez, Postdoc in the Bienko Group (Genomics), who has been awarded a prestigious Marie Skłodowska-Curie Actions Postdoctoral Fellowship from the European Union. The grant, totalling €172,750.08 and covering a two-year period, will support his groundbreaking project PRUNE – Uncovering the Proteomic Radial Organisation within the Eukaryotic Nucleus – to study how the spatial arrangement of nuclear proteins contributes to optimal cell functioning.
By developing a sophisticated in vitro system coupled with advanced imaging techniques and CRISPR genome editing, an international team of researchers from Human Technopole (Italy) and the TUD Dresden University of Technology (Germany) shows that tubulin tyrosination/detyrosination regulates the bidirectional IFT train movement and avoids collision between trains moving in opposite directions along the cilium. The research was funded by the ERC and the DFG “Physics of Life” Excellence Cluster. The results are published in Nature Communications.
The public notice for the creation of a list of lawyers, from which legal representation assignments may be drawn in the interest of the Human Technopole Foundation, is now online.
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