Precision medicine is at the heart of the future development of European healthcare. This is the indication of a roadmap presented by LifeTime ,the European consortium which sees HT amongs its associate partners.
The journal Nature published the article “LifeTime and improving European healthcare through cell-based interceptive medicine”. In the article innovators, research pioneers, clinicians, industry leaders and policy makers from all around Europe present a detailed roadmap of how to leverage the latest scientific breakthroughs and technologies over the next decade, to track, understand and treat human cells throughout an individual’s lifetime. A united vision to revolutionise healthcare.
Prof. Giuseppe Testa, Head of Research Centre for Neurogenomics, member of the Lifetime steering committee and co-authore of the report, commented: “LifeTime represents the best of the European spirit, which from frontier research on the cellular basis of human diseases now has the opportunity to gain concrete experience in the lives of patients and in the sustainability of our health systems. The pandemic reminded us of our fragility. Transforming healthcare through a precise understanding of the mechanisms by which a disease begins and develops over time in each patient remains an enormous challenge. But today we are finally beginning to see its feasibility thanks to a new research model that places the clinic at the center of three technological frontiers: organoids, models of each patient’s diseased organs, associated with the ability to analyze them over time, cell by cell, in all their dimensions, also making use of artificial intelligence. We are preparing to choose how to project our country towards rebirth through the Recovery Fund. LifeTime in this sense is a trace of how to do it, in the biomedical field, of how to open the future while remaining anchored to the needs of today that have never before appeared to us with so much drama.”
An international study coordinated by Milan’s Human Technopole, the Institute of Cancer Research (ICR) in London, and the Royal Marsden Hospital in London has shown that certain DNA fragments found in the blood of paediatric cancer patients can be used as “biomarkers” to obtain information on the characteristics of the disease and its ability to resist therapies. Analysing these fragments could represent an effective alternative to tumour tissue biopsy, a practice that is particularly difficult in children.
Human Technopole is honoured to have participated in today’s meeting at the Quirinale, where President of the Republic Sergio Mattarella welcomed a delegation from MIND on the occasion of the tenth anniversary of the universal exposition Milano EXPO 2015.
Meet Carlos Jimenez, Postdoc in the Bienko Group (Genomics), who has been awarded a prestigious Marie Skłodowska-Curie Actions Postdoctoral Fellowship from the European Union. The grant, totalling €172,750.08 and covering a two-year period, will support his groundbreaking project PRUNE – Uncovering the Proteomic Radial Organisation within the Eukaryotic Nucleus – to study how the spatial arrangement of nuclear proteins contributes to optimal cell functioning.
By developing a sophisticated in vitro system coupled with advanced imaging techniques and CRISPR genome editing, an international team of researchers from Human Technopole (Italy) and the TUD Dresden University of Technology (Germany) shows that tubulin tyrosination/detyrosination regulates the bidirectional IFT train movement and avoids collision between trains moving in opposite directions along the cilium. The research was funded by the ERC and the DFG “Physics of Life” Excellence Cluster. The results are published in Nature Communications.
The public notice for the creation of a list of lawyers, from which legal representation assignments may be drawn in the interest of the Human Technopole Foundation, is now online.
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