Zuccolo Group
Nello Zuccolo Group, epidemiologi, statistici e data scientist analizzano dati complessi altamente dimensionali per migliorare la nostra comprensione della salute materna e infantile, con particolare attenzione agli effetti intergenerazionali. Sviluppiamo nuove pipeline di dati e acquisizioni di fenotipi, applicando al contempo metodi all’avanguardia per un’inferenza capace di informare la traduzione della conoscenza. Descriviamo le tendenze e le traiettorie di salute e comportamenti che emergono nelle popolazioni contemporanee, studiamo i loro determinanti, identifichiamo i predittori di vulnerabilità e rischio e indaghiamo come le famiglie e in particolare le interazioni genitore-figlio, modellano la salute e il benessere degli individui. L’evidenza risultante aiuterà a stabilire le priorità e aiutare la progettazione di interventi a livello familiare o genitoriale per sostenere la salute materna, infantile e adolescenziale.
FINANZIAMENTI
MSCA Postdoctoral Fellowship – Albert Navarro Gallinad
ALUMNI
- Molly Van der Heiden: Bristol Medical School student intern
- Elham Bahari Kheirjoui: Università degli Studi di Milano MSc student intern
Membri del gruppo
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Luisa Zuccolo
Research Group Leader -
Maeregu Woldeyes Arisido
Postdoc -
Alice Sofia Calvello
Undergraduate Intern -
Sandra Mickwitz
Undergraduate Intern -
Albert Navarro Gallinad
Health Data Scientist -
Valeria Nazzari
PhD Student -
Linda Repetto
Genetic Epidemiologist
Pubblicazioni
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10/2022 - Addiction
Prenatal smoking, alcohol and caffeine exposure and offspring externalizing disorders: a systematic review and meta-analysis
Background and aims Several studies have indicated an association between maternal prenatal substance use and offspring externalizing disorders; however, it is uncertain whether this relationship is causal. We conducted a systematic review to determine: (1) if the literature supports a causal role of maternal prenatal substance use on offspring externalizing disorders diagnosis and (2) whether […]
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08/2022 - Cureus
The Frequency of Infant-Feeding Presentations at English Emergency Departments During the SARS-CoV-2 Pandemic: A Nation-Wide Electronic Health Records Study
Objectives: To examine the frequency and distribution of infant feeding-related presentations at emergency departments (EDs) before and during the SARS-CoV-2 pandemic. Setting: Attendances at 48 major EDs in England in two 50-week periods before and during the COVID-19 pandemic: period 1, April 2, 2019 to March 10, 2020 and period 2, April 1, 2020 to March […]
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06/2022 - The Lancet Digital Health
COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records
Background Updatable estimates of COVID-19 onset, progression, and trajectories underpin pandemic mitigation efforts. To identify and characterise disease trajectories, we aimed to define and validate ten COVID-19 phenotypes from nationwide linked electronic health records (EHR) using an extensible framework. Methods In this cohort study, we used eight linked National Health Service (NHS) datasets for people in England alive […]
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05/2022 - Addiction
Prenatal smoking, alcohol and caffeine exposure and maternal-reported attention deficit hyperactivity disorder symptoms in childhood: triangulation of evidence using negative control and polygenic risk score analyses
Background and aims Studies have indicated that maternal prenatal substance use may be associated with offspring attention deficit hyperactivity disorder (ADHD) via intrauterine effects. We measured associations between prenatal smoking, alcohol and caffeine consumption with childhood ADHD symptoms accounting for shared familial factors. Design First, we used a negative control design comparing maternal and paternal […]
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