Luisa Zuccolo
- Research Group Leader, Zuccolo Group
La dott.ssa Luisa Zuccolo è un’epidemiologa con esperienza nell’inferenza causale applicata alla salute della popolazione. Dopo la laurea in Fisica, ha ottenuto una borsa di studio presso l’Università degli Studi di Torino in Epidemiologia e Sorveglianza del Cancro. Si è poi trasferita all’Università di Bristol (Regno Unito) ed è stata insignita di una borsa di studio pre-dottorato dal Medical Research Council del Regno Unito per completare un Master in Epidemiologia (London School of Hygiene and Tropical Medicine) e un PhD in Genetic Epidemiology con il Prof. George Davey Smith (Università di Bristol). Le è stata quindi assegnata una seconda borsa di studio MRC in Population Health Science and Epidemiology; dopodiché, nel 2018, ha acquisito una posizione di ruolo presso l’Università di Bristol. La ricerca del Dr. Zuccolo include gli effetti causali dell’alcol sulla salute, in particolare dell’esposizione prenatale all’alcol, utilizzando metodi e progetti che migliorano l’inferenza causale. Più recentemente, si è concentrata sulla salute materna e infantile, studiando gli ostacoli e gli effetti dell’allattamento al seno prolungato, l’impatto del COVID-19 sugli esiti di fertilità e gravidanza e la disinformazione nei messaggi di salute pubblica sui social media.
Pubblicazioni
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01/2023 - Epidemiology
Partial Identification of the Average Causal Effect in Multiple Study Populations: The Challenge of Combining Mendelian Randomization Studies
Background: Researchers often use random-effects or fixed-effects meta-analysis to combine findings from multiple study populations. However, the causal interpretation of these models is not always clear, and they do not easily translate to settings where bounds, rather than point estimates, are computed. Methods: If bounds on an average causal effect of interest in a well-defined […]
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12/2022 - BMC Infectious Diseases
COVID-19 vaccination in pregnancy: views and vaccination uptake rates in pregnancy, a mixed methods analysis from SAIL and the Born-In-Wales Birth Cohort
Background Vaccine hesitancy amongst pregnant women has been found to be a concern during past epidemics. This study aimed to (1) estimate COVID-19 vaccination rates among pregnant women in Wales and their association with age, ethnicity, and area of deprivation, using electronic health record (EHR) data linkage, and (2) explore pregnant women’s views on receiving […]
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12/2022 - Nature
Genetic diversity fuels gene discovery for tobacco and alcohol use
Tobacco and alcohol use are heritable behaviours associated with 15% and 5.3% of worldwide deaths, respectively, due largely to broad increased risk for disease and injury1–4. These substances are used across the globe, yet genome-wide association studies have focused largely on individuals of European ancestries5. Here we leveraged global genetic diversity across 3.4 million individuals […]
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10/2022 - Journal of the American Heart Association
Alcohol Intake and Hypertensive Disorders of Pregnancy: A Negative Control Analysis in the ALSPAC Cohort
Background Alcohol intake increases blood pressure yet estimates of associations between maternal intake and hypertensive disorders of pregnancy (HDP) are sparse and range from null to a protective effect. Here we estimated the association of maternal drinking during pregnancy with preeclampsia and gestational hypertension (separately and jointly, as HDP). We used partner’s alcohol intake as […]
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10/2022 - Addiction
Prenatal smoking, alcohol and caffeine exposure and offspring externalizing disorders: a systematic review and meta-analysis
Background and aims Several studies have indicated an association between maternal prenatal substance use and offspring externalizing disorders; however, it is uncertain whether this relationship is causal. We conducted a systematic review to determine: (1) if the literature supports a causal role of maternal prenatal substance use on offspring externalizing disorders diagnosis and (2) whether […]
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