07/2020 - A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
SARS-CoV-2 has caused the COVID-19 pandemic. There is an urgent need for physiological models to study SARS-CoV-2 infection using human disease-relevant cells. COVID-19 pathophysiology includes respiratory failure but involves other organ systems including gut, liver, heart, and pancreas. We present an experimental platform comprised of cell and organoid derivatives from human pluripotent stem cells (hPSCs). […]
06/2020 - Connected from the Outside: The Role of US Regions in Promoting the Integration of the European Research System
Considerable efforts have been deployed by the European Union to create an integrated Research & Development area. In this paper, we focus on the structure and evolution of the European collaboration network as reflected by patent data. We study patent networks representing collaborations between inventors located in different geographic areas. Existing studies seem to indicate […]
06/2020 - O2S2 for the Geodata Deluge
We illustrate a fewrecent ideas of Object Oriented Spatial Statistics (O2S2), focusing on the problem of kriging prediction in situations where a global second order stationarity assumption for the random field generating the data is not justifiable or the space domain of the field is complex. By localizing the analysis through the Random Domain Decomposition […]
06/2020 - Modeling the Effect of Recurrent Events on Time-to-event Processes by Means of Functional Data
In this paper we propose a methodological framework for modeling information carried out by a longitudinal process by means of functional data, within a survival framework targeting the time-to-event process of interest. In particular, the longitudinal process is represented by the compensator of a marked point process the recurrent events are supposed to derive from. […]
06/2020 - Economic and social consequences of human mobility restrictions under COVID-19
In response to the coronavirus disease 2019 (COVID-19) pandemic, several national governments have applied lockdown restrictions to reduce the infection rate. Here we perform a massive analysis on near–real-time Italian mobility data provided by Facebook to investigate how lockdown strategies affect economic conditions of individuals and local governments. We model the change in mobility as […]
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