09/2019 - Methods to account for citation inflation in research evaluation
Quantitative research evaluation requires measures that are transparent, relatively simple, and free of disciplinary and temporal bias. We document and provide a solution to a hitherto unaddressed temporal bias – citation inflation – which arises from the basic fact that scientific publication is steadily growing at roughly 4% per year. Moreover, because the total production […]
08/2019 - Communities and regularities in the behaviour of investment fund managers
We analyze a large microlevel dataset on the full daily portfolio holdings and exposures of 22 complex investment funds to shed light on the behavior of professional investment fund managers. We introduce a set of quantitative attributes that capture essential distinctive features of manager allocation strategies and behaviors. These characteristics include turnover, attitude toward hedging, […]
08/2019 - Microridges are apical epithelial projections formed of F-actin networks that organize the glycan layer
Apical projections are integral functional units of epithelial cells. Microvilli and stereocilia are cylindrical apical projections that are formed of bundled actin. Microridges on the other hand, extend laterally, forming labyrinthine patterns on surfaces of various kinds of squamous epithelial cells. So far, the structural organization and functions of microridges have remained elusive. We have […]
08/2019 - From enhanceropathies to the epigenetic manifold underlying human cognition
A vast portion of intellectual disability and autism spectrum disorders is genetically caused by mutations in chromatin modulators. These proteins play key roles in development and are also highly expressed in the adult brain. Specifically, the pivotal role of chromatin regulation in transcription has placed enhancers at the core of neurodevelopmental disorders (NDDs) studies, ushering […]
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