Genome maps: navigating the cell nucleus with GPSeq
Researchers at Human Technopole developed a novel tool to map the spatial organisation of the nucleus of eukaryotic cells by profiling the radial distribution of the genome from the nuclear periphery to the centre. The experimental procedure is published in Nature Protocols and featured on the cover of the journal.
4 fully funded PhD scholarships in Systems Medicine
Human Technopole is offering up to 4 fully funded PhD scholarships through the SEMM PhD Program in Systems Medicine. These scholarships are open to talented and motivated graduates – both from Italy and abroad – interested in pursuing doctoral research in the following areas: Computational Biology, Functional Genomics, Population and Medical Genomics.
Human Technopole: Connecting Science Across Scales
The mechanisms of life are complex. What happens at the molecular level shapes cells, tissues, organs and entire organisms. To understand human biology, and what drives disease, we need to connect these different scales rather than study them in isolation. That is our approach at Human Technopole.
Human Technopole scales up Italian science for Europe’s health future
“Shaping the future of human health, together”: Human Technopole’s new claim was the central theme of the event held this morning at the Senate of the Republic. The conference “Human Technopole Foundation: a model of open research and innovation in the life sciences” provided an opportunity to present the third biennial Report to Parliament for 2024–2025, marking the Foundation’s definitive transition to a new phase of maturity.
Regulation of a Giant Cellular Receptor
Using structural, biochemical and computational approaches, Human Technopole researchers have uncovered how the chaperone LRPAP1 binds to Megalin and regulates its interaction with thyroglobulin and potentially other ligands. The findings are published in Communications Biology.