Jug Group awarded CZI grants to support advancement of imaging technologies
16 November 2021
Jug Group awarded CZI grants to support advancement of imaging technologies
Members of the Jug Group, Florian Jug, Joran Deschamps and Christopher Schmied, have been awarded two $20.000 grants for the creation of napari plugins. The grants are awarded by the Chan Zuckerberg Initiative (CZI) as part of a wider effort to advance technologies and expand global access to bioimaging.
napari is a community-built software used to view and analyse large multi-dimensional images. The tool enables Python practitioners, biologists, and other scientists to leverage Python’s scientific resources without the need for prior coding experience. The plugins proposed by the Jug Group will give users wide access to user-friendly cutting-edge methods for denoising and segmentation of images.
The two proposals are in line with the wider aim of the Jug Group to push the boundaries of what image analysis and Machine Learning can do for quantifying biological (image) data, by developing advanced, cutting-edge methods and sharing them with the wider research community.
To this end, and in line with Human Technopole’s mission to train the next generation of leading scientists, the Jug Group also regularly organises workshops to familiarise researchers working in life sciences with state-of-the-art deep learning techniques for microscopy image analysis, with a focus on image denoising and segmentation.
The next course “Deep learning for microscopy image analysis”, open to 24 students, will take place virtually from 22 to 26 November with the participation of lecturers from EMBL, University of Birmingham, CZ Biohub, EMBL-EBI and EPFL.
The Glastonbury Group is among the recipients of the Data Insights Cycle 3 awards. The aim of the grant is to develop a machine learning model that identifies disease-relevant cell subpopulations whilst predicting a phenotype/disease of interest from large-scale single-cell RNA-seq data.
In collaboration with an international team of scientists, HT researchers identified a missense mutation in a gene involved in brain-intrinsic immunity as the genetic cause of SARS-CoV-2 brainstem encephalitis.
A study by Human Technopole, the Institute of Cancer Research and the Royal Marsden NHS Foundation Trust in London has shown that in prostate cancer the presence in the same tumour of cells with large differences in shape and genetic composition indicates an increased risk of relapse, including after a decade. The study may help doctors better tailor treatment for this disease, adopting more aggressive therapies in cases where these parameters indicate a higher risk of disease recurrence.
Human Technopole is opening its National Facilities, providing advanced equipment and technologies accessible through calls for proposals open to the Italian scientific community. Projects will be selected by a commission of international experts. Scientists will have access to five new dedicated facilities, which act as catalysts for open innovation in the life sciences sector, crucial for research and the health of Italians.
An international team of scientists led by HT researchers Magda Bienko and Nicola Crosetto developed an open-source software for deconvolution of widefield fluorescence microscopy image stacks and large tissue scans. This new tool increases the information obtained with fluorescence microscopy-based spatial omic methods.
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