Zuccolo Group
Nello Zuccolo Group, epidemiologi, statistici e data scientist analizzano dati complessi altamente dimensionali per migliorare la nostra comprensione della salute materna e infantile, con particolare attenzione agli effetti intergenerazionali. Sviluppiamo nuove pipeline di dati e acquisizioni di fenotipi, applicando al contempo metodi all’avanguardia per un’inferenza capace di informare la traduzione della conoscenza. Descriviamo le tendenze e le traiettorie di salute e comportamenti che emergono nelle popolazioni contemporanee, studiamo i loro determinanti, identifichiamo i predittori di vulnerabilità e rischio e indaghiamo come le famiglie e in particolare le interazioni genitore-figlio, modellano la salute e il benessere degli individui. L’evidenza risultante aiuterà a stabilire le priorità e aiutare la progettazione di interventi a livello familiare o genitoriale per sostenere la salute materna, infantile e adolescenziale.
FINANZIAMENTI
MSCA Postdoctoral Fellowship – Albert Navarro Gallinad
ALUMNI
- Molly Van der Heiden: Bristol Medical School student intern
- Elham Bahari Kheirjoui: Università degli Studi di Milano MSc student intern
Membri del gruppo
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Luisa Zuccolo
Research Group Leader -
Maeregu Woldeyes Arisido
Postdoc -
Alice Sofia Calvello
Undergraduate Intern -
Sandra Mickwitz
Undergraduate Intern -
Albert Navarro Gallinad
Health Data Scientist -
Valeria Nazzari
PhD Student -
Linda Repetto
Genetic Epidemiologist
Pubblicazioni
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10/2024 - The Lancet Regional Health: Europe
COVID-19 diagnosis, vaccination during pregnancy, and adverse pregnancy outcomes of 865,654 women in England and Wales: a population-based cohort study
Background The extent to which COVID-19 diagnosis and vaccination during pregnancy are associated with risks of common and rare adverse pregnancy outcomes remains uncertain. We compared the incidence of adverse pregnancy outcomes in women with and without COVID-19 diagnosis and vaccination during pregnancy. Methods We studied population-scale linked electronic health records for women with singleton […]
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08/2024 - Nature Human Behaviour
The genetic landscape of neuro-related proteins in human plasma
Understanding the genetic basis of neuro-related proteins is essential for dissecting the molecular basis of human behavioural traits and the disease aetiology of neuropsychiatric disorders. Here the SCALLOP Consortium conducted a genome-wide association meta-analysis of over 12,000 individuals for 184 neuro-related proteins in human plasma. The analysis identified 125 cis-regulatory protein quantitative trait loci (cis-pQTL) and […]
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08/2024 - The Lancet Regional Health: Europe
COVID-19 vaccination and birth outcomes of 186,990 women vaccinated before pregnancy: an England-wide cohort study
Background COVID-19 vaccination in pregnancy is recommended by the World Health Organisation as effective and safe. However, there remains a lack of robust evidence to inform vaccination choices for women of childbearing potential in relation to their future pregnancies. Here we investigated the association between starting a course of COVID-19 vaccination before pregnancy and birth […]
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08/2024 - Alcohol: Clinical and Experimental Research
Trends in fetal alcohol spectrum disorder research: A bibliometric review of original articles published between 2000 and 2023
Fetal alcohol spectrum disorder (FASD) is a leading cause of neurodevelopmental disability globally. International organizations have highlighted an urgent need for improved prevention, diagnosis, and support. However, the evidence base needed to inform this is thought to be limited. We conducted two complementary reviews to (i) describe trends in the volume and characteristics of original […]
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