The year is off to a good start for our Structural Biology Research Centre, with the arrival of three new Group Leaders following the open recruitment call which opened in April 2020.
Francesca Coscia, an Italian biochemist and Cryo-EM expert currently at the Medical Research Council Laboratory of Molecular Biology in Cambridge, UK. Her research focuses on the molecular mechanisms behind thyroid function and disease. She has already started a collaboration with HT and will be joining full time in May 2021.
Philipp Erdmannis a German chemical biologist and microscopist. After five years as a project group leader at the Max Plank Institute for Biochemistry in Martinsried, Germany, he has joined HT in February 2021. At HT his lab will focus on the analysis of liquid-liquid phase separation (LLPS) effects using in situ cryo-electron tomography. LLPS is often involved in crucial processes of both transmittable and non-transmittable human diseases, including virus infections and neurodegenerative disorders.
Ana Casañal is a Spanish biochemist and integrated structural biology expert with a focus on Cryo-EM. Since 2014, she has been a postdoctoral researcher leading Cryo-EM projects at the Medical Research Council Laboratory of Molecular Biology in Cambridge, UK. At HT her group will combine cutting edge Cryo-EM with biochemical and biophysical methods to unravel the mechanisms of mRNA processing machines to help reveal how their deregulation impacts human disease. She will be joining HT in March 2021.
We are excited to have Francesca, Philipp and Ana join HT and we look forward to welcoming them to Milan.
The Glastonbury Group is among the recipients of the Data Insights Cycle 3 awards. The aim of the grant is to develop a machine learning model that identifies disease-relevant cell subpopulations whilst predicting a phenotype/disease of interest from large-scale single-cell RNA-seq data.
In collaboration with an international team of scientists, HT researchers identified a missense mutation in a gene involved in brain-intrinsic immunity as the genetic cause of SARS-CoV-2 brainstem encephalitis.
A study by Human Technopole, the Institute of Cancer Research and the Royal Marsden NHS Foundation Trust in London has shown that in prostate cancer the presence in the same tumour of cells with large differences in shape and genetic composition indicates an increased risk of relapse, including after a decade. The study may help doctors better tailor treatment for this disease, adopting more aggressive therapies in cases where these parameters indicate a higher risk of disease recurrence.
Human Technopole is opening its National Facilities, providing advanced equipment and technologies accessible through calls for proposals open to the Italian scientific community. Projects will be selected by a commission of international experts. Scientists will have access to five new dedicated facilities, which act as catalysts for open innovation in the life sciences sector, crucial for research and the health of Italians.
An international team of scientists led by HT researchers Magda Bienko and Nicola Crosetto developed an open-source software for deconvolution of widefield fluorescence microscopy image stacks and large tissue scans. This new tool increases the information obtained with fluorescence microscopy-based spatial omic methods.
Manage Cookie Consent
This website uses technical cookies to provide you with a better browsing experience and, subject to your consent, profiling cookies to offer you information and advertising in line with your preferences. For more details, you can consult our cookie policy by clicking on the link below, or set your preferences by clicking "set preferences". By selecting "accept cookies" you consent to the use of all types of cookies while you can revoke your consent by clicking on "refuse". By deciding to refuse or closing the banner, only the technical cookies necessary for the correct functioning of the site will be activated.
Technical cookies (required)
Always active
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Third party cookies for statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Third party cookies for profiling
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.