The year is off to a good start for our Structural Biology Research Centre, with the arrival of three new Group Leaders following the open recruitment call which opened in April 2020.
Francesca Coscia, an Italian biochemist and Cryo-EM expert currently at the Medical Research Council Laboratory of Molecular Biology in Cambridge, UK. Her research focuses on the molecular mechanisms behind thyroid function and disease. She has already started a collaboration with HT and will be joining full time in May 2021.
Philipp Erdmannis a German chemical biologist and microscopist. After five years as a project group leader at the Max Plank Institute for Biochemistry in Martinsried, Germany, he has joined HT in February 2021. At HT his lab will focus on the analysis of liquid-liquid phase separation (LLPS) effects using in situ cryo-electron tomography. LLPS is often involved in crucial processes of both transmittable and non-transmittable human diseases, including virus infections and neurodegenerative disorders.
Ana Casañal is a Spanish biochemist and integrated structural biology expert with a focus on Cryo-EM. Since 2014, she has been a postdoctoral researcher leading Cryo-EM projects at the Medical Research Council Laboratory of Molecular Biology in Cambridge, UK. At HT her group will combine cutting edge Cryo-EM with biochemical and biophysical methods to unravel the mechanisms of mRNA processing machines to help reveal how their deregulation impacts human disease. She will be joining HT in March 2021.
We are excited to have Francesca, Philipp and Ana join HT and we look forward to welcoming them to Milan.
The Social Innovation Campus 2026 was a great success, bringing thousands of students to MIND to discuss social innovation, sustainability and the future of work. From 25 to 27 February, young people engaged with organisations, institutions and companies to explore how innovation can generate social impact. Human Technopole contributed to this collective effort through different voices and perspectives.
Are you passionate about AI, mathematical modelling, or genomics, and eager to work on high-impact research in biomedical science? Human Technopole is excited to offer four fully-funded PhD positions as part of the prestigious PhD Programme in Data Analytics and Decision Sciences of the Politecnico di Milano.
Lorenzo Calviello and his group of the Human Technopole’s Research Centres for Genomics and Computational Biology have been awarded a five-year My First AIRC Grant by Fondazione AIRC per la Ricerca sul Cancro. The grant provides over €99,000 for 2026, for a total of €500,000, to support a project aimed at identifying cancer-specific proteins that could serve as new immunotherapy targets in colorectal cancer.
Human Technopole researchers have identified the molecular mechanisms by which the membrane receptor sortilin binds thyroglobulin along its pathway to the release of thyroid hormones within the thyroid gland. The results of the research were published in Nature Communications and highlight that sortilin senses thyroglobulin via a short flexible “tag” which appears to be a common motif for the recognition of other partner proteins throughout our body.
The AI4Life project, co-led by Florian Jug (Computational Biology Research Centre at Human Technopole) and Anna Kreshuk (EMBL), received the highest possible score in the European Commission’s final review, recognising its scientific impact and the quality of its achievements in applying artificial intelligence to biological image analysis.
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